International Session 42　　Basic (Cancer) 1

AimsTo correlate clinicoradiological findings of cartilage involvement with histopathology for laryngeal and hypopharyngeal cancers.MethodologyThis was a retrospective study of 143 patients from year 2010 to 2019.ResultsThe mean age of the population was 53 years(15-69)with a Male to female ratio of 3 : 1(108 : ３ ５) .The epicenter was Larynx in 97 and Hypopharynx in 46 patients.Dysphagia(48)was the most common symptom followed by hoarseness of voice(65) .Six patients had prior tracheostomy.Majority had PDSCC(70, 49％)or MDSCC(70, 49％) .Three(2％)had WDSCC.The major indication for surgery was cartilage erosion(90％) , non-functional larynx(8％)and extra-laryngeal spread without cartilage erosion(2％) .The histopathological cartilage erosion was present in 75％ patients.Thyroid cartilage was eroded in 99, thyroid/arytenoid in 2, thyroid/arytenoid/cricoid in 1 and thyroid/cricoid in 5 patients.Adjuvant Radiotherapy was received by 68 and Concurrent Chemoradiotherapy in 65 patients.Majority of the patients were alive(91, 64％)at a median follow up of 28 months.ConclusionOur study shows utility of CT scan in assessing cartilage erosion and extralayngeal extension of disease.