Case report reveals a conjunctival stromal tumor in a young girl, suggesting important diagnostic considerations.
: Purpose To report an unusual case of conjunctival stromal tumor (COST) located in the punctum of the eyelid in an 18-month-girl. Observation The patient is an 18-month female, with no significant medical history or ocular trauma, who presented with a slowly growing mass on the punctum of her right-upper eyelid. Ophthalmic exam showed that the lesion was not attached to the globe of the eye. The lesion was completely surgically excised. Histopathological analysis showed a well-circumscribed polypoid nodule comprised of bland spindled cells with pseudonuclear inclusions and giant cells with floret-like nuclear configurations. The immunohistochemical staining pattern was consistent with COST. Conclusion COST is an emerging entity first described in 2012 and rarely reported in children. Herein, we report the third diagnosis of COST in a child, the youngest age reported to date. As such, it should be considered in the differential diagnosis of a conjunctival lesion regardless of age. In the differential diagnosis, it is important to distinguish COST from conjunctival myxoma given the syndromic associations of the latter.
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Dai et al. (2026) studied this question.
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