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Demonstrates efficient prediction of transcription factor binding in genomic data, indicating powerful analytical tools.
Summary SEMPLR is an R package that predicts transcription factor binding and variant effects using SNP Effect Matrices (SEMs), providing efficient, genome-wide scoring, enrichment testing, and visualization tools for comprehensive analysis of regulatory sequences. Availability Available on GitHub at https://github.com/grkenney/SEMPLR and on Bioconductor at https://bioconductor.org/packages/release/bioc/html/SEMPLR.html. Supplementary information Supplementary data are available at Bioinformatics online.
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Kenney et al. (2026) studied this question.
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