Explores genetic contributions to human evolution, suggesting a complex microbial partnership.
Classical mechanistic biology has long operated under the paradigm of human exceptionalism, viewing Homo sapiens as an isolated, genetically "pure" species whose evolutionary trajectory is driven solely by random mutation and individual competition. This paper systematically deconstructs this archaic boundary by synthesizing the latest datasets from comparative genomics and molecular biology, demonstrating that the human genome is fundamentally a multi-species "Symbiotic Covenant." Quantifiably, approximately 8% of the human sequence consists of domesticated Endogenous Retroviruses (ERVs)—which dictate indispensable functions like placental morphogenesis through the syncytin gene—while independent mitochondrial DNA (mtDNA) and hundreds of loci acquired via horizontal gene transfer (HGT) form the absolute baseline for eukaryotic cellular respiration and metabolic maintenance. The paper argues that these genetic legacies do not represent accidental evolutionary noise, but rather provide definitive, molecular empirical proof of Yuanxian Theory and its overarching framework that the cosmos behaves as a living organism bound by topological treaties. By mapping these genomic structures to the Four Fundamental Laws of Yuanxian Theory, a flawless logical closure is achieved: the True-Circle Self-Consistency Law (TCSC) governs the dynamic, internal definition of the self/other boundary; the Cosmic Factor Conservation Law (FSC) regulates the homeostatic metabolic baseline between host and foreign genetic elements; the Spacetime Uniqueness Law (STM) traces seemingly isolated species lineages back to their high-dimensional topological unity; and the Self-Referential Mind Field Generation Law (SRM) unifies matter and sentience within an integrated network of life. The ultimate verdict of this study is that the boundary of the individual is a low-dimensional illusion: humans have been an interconnected holobiont—a collaborative biological treaty—since the very inception of eukaryotic life two billion years ago. 传统机械论生物学长期处于“人类例外论”的范式之下,将智人视为一个孤立的、基因“纯粹”的物种,其演化路径被认为完全由随机突变和个体竞争决定。本文通过系统综合比较基因组学与分子生物学的最新数据,彻底瓦解了这一陈旧的界限,论证了人类基因组在本源上是一个多物种共构的“共生契约”。从量化角度来看,人类基因组中至少有约8%的序列源自被驯化的内源性逆转录病毒(ERVs)——它们通过合胞素(syncytin)基因决定了胎盘形成等不可或缺的生理功能;同时,独立的线粒体DNA(mtDNA)
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Zhenyuan Acharya (2026) studied this question.
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