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This research examines enterococcal infections in LVAD recipients, focusing on their clinical implications and treatment failures.

June 14, 2026PathogensOpen Access

Enterococcal Infections in Left Ventricular Assist Device Recipients: Two Clinical Cases and Systematic Review

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This research examines enterococcal infections in LVAD recipients, focusing on their clinical implications and treatment failures.
Two clinical cases of Enterococcus faecalis LVAD infection reported.
A PRISMA-based systematic review of cases from 1996 to 2025 published in PubMed/MEDLINE was conducted.
Primary outcomes included clinical cure, relapse or recurrence, mortality, and device removal.
E. faecalis accounted for 47% and E. faecium for 29% of infections in 17 analyzed cases.
Bacteremia was present in 76% of cases; LVAD-associated endocarditis occurred in 18%.
Recurrence or relapse and overall mortality were each reported in 18% of patients.

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Randomized trial reports enterococcal infection outcomes in LVAD recipients, suggesting challenges in treatment.

Gay et al. (2026) studied this question.

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