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June 14, 2026Critical Reviews in Analytical ChemistryOpen Access

From Sampling to Screening: A Review of Targeted and Non-Targeted PFAS Analysis in Environmental Samples

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Authors

MHMagdalena HerokSilesian University of TechnologyHBHanna BarchañskaSilesian University of TechnologyMPMonika PartykaAnalytical Services

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Overview

This review examines PFAS determination methods, focusing on screening strategies and analytical challenges.

Key Points

  • The aim is to evaluate current methodologies for analyzing PFAS in environmental samples.
  • Critically reviews targeted and non-targeted analytical strategies for PFAS.
  • Discusses liquid chromatography coupled to tandem mass spectrometry as the standard method.
  • Analyzes high-resolution mass spectrometry workflows for identifying diverse PFAS compounds.
  • Targeted LC-MS/MS is limited to predefined compound lists, hindering comprehensive analysis.
  • Non-targeted and suspect screening methods enable the discovery of unrecognized PFAS compounds.
  • Harmonized sampling protocols and quality assurance measures are essential for reliable PFAS monitoring.

Cite This Study

Herok et al. (2026) studied this question.

synapsesocial.com/papers/6a2e4753b1cc60ccdea8be82https://doi.org/10.1080/10408347.2026.2685273
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