What is the clinical evidence from this study?

Study design: Case Report. Population: Raghib syndrome (n=1). Intervention: Conservative management with anticoagulation.

What does this research mean for the field?

Conservative management with anticoagulation is a safe and effective alternative to surgical intervention for patients with Raghib syndrome who have minimal right-to-left shunting and lack cyanosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to elucidate the physiological aspects of Raghib syndrome through multimodal cardiac imaging. It also seeks to evaluate management strategies for affected patients.

June 14, 2026JACC Case ReportsOpen Access

Raghib Syndrome Physiology Revealed by Multimodality Cardiac Imaging

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Key result

Conservative anticoagulation appears safe and effective for Raghib syndrome with minimal right-to-left shunting.

Key Points

This research aims to elucidate the physiological aspects of Raghib syndrome through multimodal cardiac imaging. It also seeks to evaluate management strategies for affected patients.
Utilized multimodal cardiac imaging techniques including computed tomography, transesophageal echocardiography, and magnetic resonance imaging.
Analyzed anatomical features and flow dynamics in a 60-year-old woman diagnosed with Raghib syndrome.
Managed the condition conservatively with anticoagulation and scheduled follow-ups.
Confirmed the presence of bilateral superior vena cavae and minimal right-to-left shunting (3%).
Demonstrated that conservative management was effective for patients without cyanosis, avoiding the need for surgical intervention.
Highlighted the importance of multimodal imaging for accurate diagnosis and monitoring of congenital heart anomalies.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 60-year-old woman with Raghib syndrome presenting with palpitations due to atrial flutter.

Intervention

Multimodality cardiac imaging (computed tomography, transesophageal echocardiography, and magnetic resonance imaging) and conservative management with anticoagulation

Outcome

Diagnosis and characterization of anatomy and flow dynamics

Multimodality imaging is crucial for diagnosing Raghib syndrome and characterizing flow dynamics, which can safely guide conservative management with anticoagulation in non-cyanotic patients.

Discussion

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Implication

Multimodality imaging aids diagnosis of Raghib syndrome in adults with atrial flutter; leaves open optimal management strategies.

Cite This Study

Panigrahy et al. (2026) conducted a case report in Raghib syndrome (n=1). Conservative management with anticoagulation was evaluated. Conservative management with anticoagulation was safe and effective for a 60-year-old woman with Raghib syndrome and minimal right-to-left shunting.

synapsesocial.com/papers/6a2e47cdb1cc60ccdea8c464 https://doi.org/10.1016/j.jaccas.2026.108809

Topics

Congenital heart disease adults

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Raghib Syndrome Physiology Revealed by Multimodality Cardiac Imaging

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Topics

Raghib Syndrome Physiology Revealed by Multimodality Cardiac Imaging

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider