What question did this study set out to answer?

The review aims to highlight the use of deep eutectic solvents in multicomponent reactions for the synthesis of bioactive heterocycles.

June 14, 2026Green Processing and SynthesisOpen Access

Deep eutectic solvents as green catalysts for multicomponent reactions: a sustainable approach to heterocyclic synthesis

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Authors

KVK. VenkatesanRajiv Gandhi University MZMagdi E. A. ZakiImam Mohammad ibn Saud Islamic University KMKadeer MohamadRajiv Gandhi University

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Implication

Review summarizes advances in deep eutectic solvents promoting heterocyclic synthesis via multicomponent reactions, indicating a sustainable approach.

Key Points

The review aims to highlight the use of deep eutectic solvents in multicomponent reactions for the synthesis of bioactive heterocycles.
Summarized recent advances in DES applications from 2019 to 2025.
Critically evaluated examples of DES-mediated synthesis of various heterocycles.
Addressed challenges and perspectives for improving substrate diversity and integrating biocatalysis.
DESs significantly accelerate C–C and C–heteroatom bond-forming reactions in heterocycle synthesis.
Reported advantages of DESs include biodegradability, low toxicity, and enhanced reaction rates.
Emphasized the need for optimizing DES structures and expanding their applications in sustainable drug discovery.

Cite This Study

Venkatesan et al. (2026) studied this question.

synapsesocial.com/papers/6a2e47f9b1cc60ccdea8c4d3 https://doi.org/10.1515/gps-2025-0170

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Implication

Review summarizes advances in deep eutectic solvents promoting heterocyclic synthesis via multicomponent reactions, indicating a sustainable approach.

Deep eutectic solvents as green catalysts for multicomponent reactions: a sustainable approach to heterocyclic synthesis

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Implication

Key Points

Cite This Study

Deep eutectic solvents as green catalysts for multicomponent reactions: a sustainable approach to heterocyclic synthesis

Discussion

Member takes

Implication

Key Points

Cite This Study

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