What question did this study set out to answer?

Evaluate the safety and midterm efficacy of the Pipeline embolization device for treating wide-necked cerebral aneurysms.

April 1, 2009Neurosurgery

Curative Endovascular Reconstruction of Cerebral Aneurysms With the Pipeline Embolization Device

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Randomized trial demonstrates effective occlusion of large and giant aneurysms, suggesting a safe treatment option.

Evaluate the safety and midterm efficacy of the Pipeline embolization device for treating wide-necked cerebral aneurysms.
Treat 53 patients with large and giant wide-necked intracranial aneurysms using the Pipeline embolization device (PED).
All patients pretreated with dual antiplatelet medications for at least 72 hours before surgery.
Follow-up digital subtraction angiograms performed at 3, 6, and 12 months post-treatment.
Complete angiographic occlusion achieved in 95% of aneurysms at 12 months (n=18).
No major complications, including stroke or death, reported during the study.
Transient symptoms resolved within 1 month for 5% of patients with giant aneurysms.

Lylyk et al. (2009) studied this question.

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