Key result
Placenta accreta spectrum arises from prior uterine surgery damage rather than primary placental anomalies.
Why the study?
Emerging evidence challenges the long-held pathophysiological understanding of placenta accreta spectrum, suggesting a critical reassessment of its definition, diagnosis, and management is overdue.
This perspective challenges the traditional understanding of placenta accreta spectrum as an invasive disease, redefining it as a consequence of uterine scarring and calling for more conservative management strategies.
Placenta accreta spectrum (PAS) is a serious pregnancy complication caused by abnormal placental attachment to the uterus. In this Perspective, Eric Jauniaux and colleagues discuss emerging evidence that challenges our long-held pathophysiological understanding of PAS, and argue that a critical reassessment of definition, diagnosis, and management is overdue.
No takes yet. Share an insight, caveat, or question.
Jauniaux et al. (2026) conducted an editorial in Placenta accreta spectrum (PAS). Placenta accreta spectrum is increasingly understood not as a primary anomaly of placental development, but as a consequence of implantation in a uterine wall permanently damaged by prior surgery.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: