What is the clinical evidence from this study?

Study design: Other. Population: Hypertension (n=63). Intervention: Multicomponent support intervention vs. No intervention. Primary outcome: Medication adherence self-efficacy score (Cohen's d 0.87, p=<0.001).

June 14, 2026Scientific Reports0 citationsOpen Access

Effect of multicomponent support intervention on medication adherence and self-efficacy levels in hypertension patients

Q: What are the key findings of this study?

A multicomponent support intervention significantly improved medication adherence self-efficacy scores (Cohen's d 0.87, p<0.001) compared to no intervention in patients with hypertension.

Q: What question did this study set out to answer?

The study investigates the effect of a multicomponent support intervention on medication adherence and self-efficacy among hypertensive patients.

ENElif Nur NoyanState Hospital BÇBahar ÇiftçiErzurum Technical University

Key Result

A multicomponent support intervention significantly improved medication adherence self-efficacy scores (Cohen's d 0.87, p<0.001) compared to no intervention in patients with hypertension.

Key Points

The study investigates the effect of a multicomponent support intervention on medication adherence and self-efficacy among hypertensive patients.
Quasi-experimental controlled study conducted in Turkey with 63 hypertensive patients assigned to intervention and control groups.
Intervention included training on blood pressure self-monitoring and supportive measures like SMS reminders and follow-up calls.
Data were collected using self-efficacy and medication adherence scales pre- and post-intervention.
Post-test medication adherence self-efficacy scores were 45.97±5.86 in the intervention group vs. 39.75±5.57 in the control group (p<0.001, Cohen’s d=0.87).
General self-efficacy scores were 81.16±19.18 vs. 74.53±11.30 (p=0.048, Cohen’s d=0.51).
The intervention group observed significant reductions in systolic and diastolic blood pressure and body mass index (p < 0.001) over time.

Structured PICO

Does a multicomponent support intervention improve medication adherence self-efficacy and general self-efficacy in patients with hypertension?

Population

63 adult patients with hypertension on stable medication, free of cognitive issues, followed for 3 months to evaluate a multicomponent support intervention.

Intervention

Multicomponent support program including a 30-minute individualized education session on blood pressure monitoring using a 'Hypertension Education Booklet', home blood pressure monitoring twice daily, SMS reminders three times per week, and monthly follow-up calls for three months.

Comparator

No intervention (standard care), with post-test forms completed online.

Outcome

Medication adherence self-efficacy (measured by the Medication Adherence Self-Efficacy Scale in Hypertensive Patients) and general self-efficacy (measured by the General Self-Efficacy Scale) at 3 months.patient reported

A multicomponent support intervention including education, home blood pressure monitoring, and SMS reminders significantly improved medication adherence self-efficacy and general self-efficacy in hypertensive patients.

Main Result

Standardized Mean Difference: 0.87

Absolute Event Rate: 45.97% vs 39.75%

p-value: p=<0.001

Limitations

Non-random allocation approach may have introduced selection bias
No allocation concealment
Post-test data collected online whereas pre-test data were collected face-to-face
Attrition rate during follow-up
Small sample size and single-center design limit generalizability
Intervention fidelity was not formally evaluated
Multicomponent nature limits ability to determine which specific component contributed most to outcomes
Confidence intervals were not reported for all analyses

Abstract

This study aims to investigate the impact of a multicomponent support intervention on medication adherence and self-efficacy levels among patients with hypertension. This quasi-experimental controlled study was conducted in Turkey with 63 hypertensive patients assigned to intervention and control groups using a non-random allocation approach. Pre-test data were collected face-to-face. The intervention group received structured training on blood pressure self-monitoring using the “Hypertension Training Manual” and measured their blood pressure twice daily at home. Data were collected using the General Self-Efficacy Scale and the Medication Adherence Self-Efficacy Scale in Hypertensive Patients. The intervention consisted of a multicomponent support program including individualized education, a hypertension education booklet, home blood pressure monitoring, SMS reminders, and monthly follow-up calls. To support adherence, SMS reminders were sent three times per week for three months. Post-test data were collected online, and outcome assessments and statistical analyses were conducted by a researcher who was not involved in the intervention process. Post-test medication adherence self-efficacy scores were significantly higher in the intervention group than in the control group (45.97±5.86 vs. 39.75±5.57, p<0.001, Cohen’s d=0.87). General self-efficacy scores were also significantly higher in the intervention group compared with the control group (81.16±19.18 vs. 74.53±11.30, p=0.048, Cohen’s d=0.51). Statistically significant reductions in systolic and diastolic blood pressure and body mass index were observed over time in the intervention group (p < 0.001), whereas no significant differences were observed in the control group.A multicomponent educational and behavioral support intervention may contribute to improved medication adherence and self-efficacy among patients with hypertension.

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