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March 31, 2009African Journal of Biochemistry ResearchOpen Access

Diabetic patients had lower mean total cholesterol, triglycerides, and LDL-C levels compared to healthy controls, though these differences were not statistically significant (P > 0.05).

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Why the study?

Does the lipid profile differ between diabetic patients and healthy controls?

Population

50 known diabetic patients and 50 healthy subjects attending Nigerian National Petroleum Corporation Clinic…

Design

Case-control

Key result

Diabetic patients had lower mean total cholesterol, triglycerides, and LDL-C levels compared to healthy controls, though these differences were not statistically significant (P > 0.05).

Authors

CUC. E. UgwuLEL.U.S. EzeanyikaMDMoses Alilu Daikwo

Discussion

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Overview

Nonsignificant lipid differences in this case-control study should not change practice; leaves open diabetes-lipid associations in larger cohorts.

Study Design

Type

Case-Control (n=100)

Multicenter

No

Structured PICO

Does the lipid profile differ between diabetic patients and healthy controls?

P
Population
100 participants comprising 50 known diabetic patients and 50 healthy controls evaluated for lipid profiles.
C
Comparator
Healthy controls
O
Outcome
Lipid profile including Total cholesterol (TC), Triacylglycerols (TG), Low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C)surrogate

Main Result

p-value: p=> 0.05

Diabetic patients demonstrated better lipid profiles than healthy controls, likely reflecting the effectiveness of their ongoing medical management.

Cite This Study

Ugwu et al. (2009) conducted a case-control in Diabetes (n=100). Diabetes vs. Healthy controls was evaluated on Mean TC, TG, and LDL-C levels (p=> 0.05). Diabetic patients had lower mean total cholesterol, triglycerides, and LDL-C levels compared to healthy controls, though these differences were not statistically significant (P > 0.05).

synapsesocial.com/papers/6a2f161907eb5983fcd171b8https://doi.org/10.5897/ajbr.9000159
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lipid profile of type 2 diabetic patients at a rural tertiary hospital in Nigeria2010 · 13 citations
  2. 2Pattern of dyslipidemias in male type 2 diabetic patients in Kano, Nigeria2025
  3. 3Prevalence, treatment rates and control of dyslipidemia among diabetes patients in northern Nigeria: A cross-sectional, multicenter study2026
  4. 4Association of body mass index and abdominal adiposity with atherogenic lipid profile in Nigerians with type 2 diabetes and/or hypertension2013 · 11 citations
  5. 5Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan2026