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Integrated cytogenomic analysis is required to properly evaluate acquired ring chromosomes (aRCs) in hematological malignancies for accurate diagnostic interpretation and to elucidate molecular mechanisms of disease. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Acquired ring chromosomes in hematological malignancies: A systematic evidence review for diagnostic advances, cytogenomic insights, and clinical significance by an International Consortium on Human Ring Chromosomes (ICHRC) working group

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