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Case describes progressive enlargement of cerebellar hemangioblastomas in a patient with von Hippel-Lindau disease, indicating disease progression.
Fig. 1 Head MRI follow-up and abdominal CT findings.Axial CET 1 WI (contrast-enhanced T 1 -weighted image) obtained on admission (A) shows a cystic lesion with a solid enhancing component (arrow).Contrast-enhanced abdominal CT image (B) reveals multiple pancreatic cysts (arrowheads).Follow-up CET 1 WIs obtained at 15 months after admission (C, D) demonstrate a markedly enlarged cystic lesion in the right cerebellum (arrowhead in C) and an enhancing nodular lesion in the dorsal left cerebellum (arrowhead in D).At 26 months after admission, CET 1 WIs (E, F) show further enlargement of the dorsal left cerebellar lesion (arrowhead in F), while the ventral left cerebellar lesion shows only slight interval growth (arrows in A, C, E).R: Right side of the brain.VHL 病における多発小脳血管芽腫の増大
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Hayashi et al. (2026) studied this question.
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