A case of anti-Kelch-like protein 11 (KLHL11) antibody-positive opsoclonus-myoclonus syndrome associated with small cell lung cancer that improved after immunotherapy and cancer treatment
Case report shows neurological symptoms improved in a patient with opsoclonus-myoclonus syndrome after immunotherapy and cancer treatment.
Key Points
This case report aims to illustrate the relationship between KLHL11 antibodies and opsoclonus-myoclonus syndrome in the context of small cell lung cancer.
68-year-old female presented with ophthalmoplegia and tremors diagnosed with KLHL11 antibody-positive opsoclonus-myoclonus syndrome.
Received immunotherapy along with chemotherapy for small cell lung cancer.
Monitored improvement in neurological symptoms and performance status post-treatment.
Significant tumor reduction observed with treatment, improving neurological symptoms and performance status from 4 to 3.
Patient's condition showed marked improvement in stability and reduced tremor intensity.