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June 1, 2026European Respiratory Journal

Precision medicine in the era of CFTR modulator therapy: what comes next?

José Fontoura‐Matias Hartmut Grasemann

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Key Points

This research aims to explore the implications of CFTR modulator therapy on managing cystic fibrosis and inform future precision medicine strategies.
Examined the effects of CFTR modulator therapy on various organ systems affected by cystic fibrosis.
Evaluated the impact on chloride ion transport across membranes in patients with cystic fibrosis.
Increased chloride ion transport was observed in patients receiving CFTR modulator therapy.
Improved organ function was noted, particularly in the lungs and pancreas, post-treatment.

Implication

Examines CFTR modulator therapy impact on cystic fibrosis, suggesting future directions for precision medicine.

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Cite This Study

Fontoura‐Matias et al. (2026) studied this question.

synapsesocial.com/papers/6a2f96eca1cfeec4908280d6 https://doi.org/10.1183/13993003.00247-2026

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