Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer

June 1, 2026Cancer MedicineOpen Access

View Full Paper

Ask AI

Bookmark

Share

Key Points

This study aims to evaluate the genomic profiles of biliary tract cancer (BTC) to support precision medicine advancements.
134 BTC patients underwent genomic analysis using targeted panel sequencing.
Patients' clinicopathologic data were integrated with genomic testing results.
Genomic alterations were compared with western BTC cohorts using public NGS data.
Most frequent alterations in the cohort were TP53 (55.5%), KRAS (38.1%), ARID1A (17.2%), and CDKN2A (15.7%).
Higher prevalence of TP53, KRAS, and LRP1B in Chinese patients compared to Western BTCs.
Significant genomic alterations influenced progression-free survival and overall survival.

We only have this paper's title and publication details.

Evaluates genomic alterations in biliary tract cancer, suggesting implications for precision medicine.

No takes yet. Share an insight, caveat, or question.

Yang et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Share