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June 15, 2026The Saudi Journal of Forensic Medicine and Sciences

Re-defining Organ Weights in the Era of Virtopsy: Systematic Review of Postmortem Computed Tomography Volumetry versus Autopsy

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Authors

AAAbdulkreem Al-JuhaniKing Abdulaziz UniversityABAbdulaziz A. BinshalhoubRiyadh Elm UniversityNANaifAbdulaziz AljohaniRiyadh Elm University

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Implication

Systematic review evaluates PMCT volumetry versus autopsy for organ weight assessment, highlighting strengths and challenges.

Key Points

  • This review aims to evaluate the effectiveness of PMCT-derived organ volumes as compared to traditional autopsy weights in forensic pathology.
  • Conducted a systematic review following PRISMA 2020 and COSMIN guidance
  • Included eleven studies published from 2014 to 2022 comparing PMCT and autopsy weights
  • Examined organ volumetry for liver, heart, lungs, and spleen in adult decedents.
  • Liver and heart volumetry showed strong correlation with autopsy weights (r 0.90–0.95, R2 0.74–0.93)
  • Lung models achieved predictive performance (R2 0.84–0.91), but increased variability for affected conditions like edema
  • Overall, PMCT is a reproducible method that serves as a surrogate for autopsy weights, but variability exists for lung and spleen due to postmortem changes.

Cite This Study

Al-Juhani et al. (2026) studied this question.

synapsesocial.com/papers/6a2f980ca1cfeec4908291a8https://doi.org/10.4103/sjfms.sjfms_12_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Virtopsy, a New Imaging Horizon in Forensic Pathology: Virtual Autopsy by Postmortem Multislice Computed Tomography (MSCT) and Magnetic Resonance Imaging (MRI)—a Feasibility Study2003 · 751 citations
  2. 2The PRISMA 2020 statement: an updated guideline for reporting systematic reviews2021 · 107,043 citations
  3. 3Interrater reliability: the kappa statistic2012 · 20,240 citations
  4. 4COSMIN Risk of Bias checklist for systematic reviews of Patient-Reported Outcome Measures2017 · 2,588 citations
  5. 5Postmortem Changes as Documented in Postmortem Computed Tomography Scans2016 · 13 citations