Key result
Being physically wounded or injured in action during World War II was associated with a 1.7-fold increased risk of late-life coronary heart disease mortality over a 28-year follow-up.
Why the study?
Does being physically wounded or injured in war increase long-term coronary heart disease mortality in male veterans alive at age 55?
Cohort (n=667)
No
Does being physically wounded or injured in war increase long-term coronary heart disease mortality in male veterans alive at age 55?
Physical trauma and injury during young adulthood in war is associated with a 1.7-fold increased risk of late-life coronary heart disease mortality.
Answers are grounded in this paper and cite their sources.
Should not yet change veteran CHD risk assessment; leaves open whether early trauma causally elevates late mortality.
BACKGROUND: Wartime stress has been associated with increased late-life mortality of all causes of death. We evaluated whether wounded Finnish World War II veterans who were alive at the age of 55 have increased long-term coronary heart disease (CHD) mortality. METHODS: Health survey data were recorded in 1980 from 667 men, aged 55 years. Of them 102 had been wounded or injured in action during 1939-1945. The remaining participants served as the comparison group. The death certificates during a 28-year follow-up were obtained from the national statistics centre. Statistical comparisons were done by Cox proportional hazard regression model. RESULTS: There were altogether 140 deaths from CHD. In men who had been wounded or injured in action the crude CHD mortality rate per 10,000 population was 2843, while in the comparison group the corresponding figure was 1961. Men who had been wounded or injured in action were 1.7 times (95% CI 1.1-2.5; p = 0.01) more likely to die from CHD than the comparison group. CONCLUSIONS: Physical trauma at young adulthood may extend to lifelong effects on health. This study suggests that being physically wounded or injured in war may lead to increased CHD mortality in late adulthood in a Finnish population.
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Kunnas et al. (2011) conducted a cohort in Coronary heart disease (n=667). Wounded or injured in action during World War II vs. Not wounded or injured in action was evaluated on Coronary heart disease mortality (HR 1.7, 95% CI 1.1-2.5, p=0.01). Being physically wounded or injured in action during World War II was associated with a 1.7-fold increased risk of late-life coronary heart disease mortality over a 28-year follow-up.
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