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ADHD is a neurodevelopmental condition marked by persistent symptoms of inattention, hyperactivity, and impulsivity. The gold standard pharmacotherapy for the treatment of ADHD is CNS psychostimulants. However, a shortage of CNS psychostimulants used for the treatment of ADHD has persisted since 2022, and many patients have been forced to switch medications or have been unable to obtain medication at all, raising concerns about symptom management and quality of life. This case report describes a 30-year-old female who was unable to obtain lisdexamfetamine amid the shortage, found mixed amphetamine salts ineffective, but found success with immediate-release dextroamphetamine sulfate, a less frequently used amphetamine. This report serves to demonstrate that immediate-release dextroamphetamine sulfate may be a viable alternative stimulant to address the shortage; however, more research must be conducted to confirm these findings.
Singer et al. (Sun,) studied this question.