Incidental Serous Tubal Intraepithelial Carcinoma: A Case Report

High-grade pelvic serous carcinoma (HGSC) is the most common type of pelvic cancer among females. Serous tubal intraepithelial carcinoma (STIC) is an established precursor of HGSC, albeit rare and underdiagnosed. Its incidence ranges from <0.01% to 3% in BRCA carriers or those with a strong family history of breast or ovarian cancer. A 32 32-year-old P2L2 female underwent bilateral tubectomy for family planning, with no known family history of cancer. Histopathological examination of the fallopian tube revealed unilateral STIC. Incidental STIC mandates prolonged follow-up. Diagnosing tubal precursor lesions (such as SCOUT, STIL, STIC) to HGSC is crucial in identifying at-risk patients. The SEE-FIM protocol, along with a low immunohistochemistry threshold, is recommended. Due to its rarity and challenging diagnostic criteria, a high degree of suspicion on the part of pathologists and adequate follow-up are essential to reduce morbidity and mortality.