This paper presents an implantable bio-impedance measurement system for cardiac pacemakers. The fully integrated system features a low power analog front-end and pulse width modulated output. The bio-impedance readout benefits from voltage to time conversion to achieve a very low power consumption for wirelessly transmitting the data outside the body. The proposed IC is fabricated in a 0.18 μm CMOS process and is capable of measuring the bio-impedance at 2 kHz over a wide dynamic range from to with accuracy and maximum current injection while consuming just from a 1 V supply.
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Zamani et al. (2018) studied this question.
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