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June 17, 2026NutritionOpen Access

Dietary Inadequacy, Inflammation, and Micronutrient Status in Pregnant Women in South Africa: Evidence of a Triple Burden

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Authors

MSMarita SerfonteinMNMariëtte NelCWCorinna M. Walsh

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Overview

Baseline analysis identifies mutual impacts of dietary inadequacy and inflammation on micronutrient status in pregnant women, suggesting urgent intervention needs.

Key Points

  • This study aims to investigate how dietary inadequacy, food insecurity, and inflammation affect micronutrient status in pregnant women in South Africa.
  • Cross-sectional analysis of 205 pregnant women in Kroonstad (≤21 weeks’ gestation)
  • Assessment of dietary intake, food security, BMI, and haematological biomarkers
  • Inflammation adjustment of micronutrient biomarkers.
  • 25.4% of women were underweight and 25.8% overweight/obese based on gestational BMI.
  • 71.8% of participants showed elevated C-reactive protein levels indicating inflammation.
  • More than 95% reported inadequate iron and calcium intake, with 52.1% exhibiting iron-deficient erythropoiesis.

Cite This Study

Serfontein et al. (2026) studied this question.

synapsesocial.com/papers/6a3239f6d50b63ecad20532dhttps://doi.org/10.1016/j.nut.2026.113329
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Burden and determinants of malnutrition among pregnant women in Africa: A systematic review and meta-analysis2019 · 177 citations
  2. 2The relationship between pre-pregnancy BMI, gestational weight gain and neonatal birth weight: a retrospective cohort study2019 · 43 citations
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  4. 4Exploration of thyroglobulin as a biomarker of iodine status in iodine-sufficient and mildly iodine-deficient pregnant women2023 · 9 citations
  5. 5Global trends in dietary micronutrient supplies and estimated prevalence of inadequate intakes2017 · 433 citations