Case report shows successful treatment of recurrent corneal erosion in a patient with epidermolysis bullosa, indicating a potential new therapeutic option.
PURPOSE: Report of a case of bilateral recurrent corneal erosion syndrome (RES) resistant to conventional treatment in a patient with epidermolysis bullosa junctional type (EBJ) who was treated successfully with diamond burr keratectomy (DBK). METHODS: A 34-year-old female with EBJ presented with RES in both eyes unresponsive to intensive lubrication and bandage contact lenses. Given the persistent symptoms, DBK was performed on the left eye in August 2022 and on the right eye in January 2023. Immediate postoperative care included bandage contact lenses, prophylactic antibiotics, and gradual tapering of lubrication therapy. RESULTS: The procedures were uneventful, with complete resolution of symptoms and no recurrence after a follow-up period of up to 30 months. Examination showed clear corneas with intact epithelial integrity. Her visual acuity improved, and lubrication therapy was discontinued. CONCLUSIONS: DBK may be considered a safe and effective treatment option for managing refractory RES in patients with EBJ, providing sustained relief where conventional therapies fail.
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Sasportas et al. (2026) studied this question.
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