Atypical and Varied Presentations of Ameloblastoma: A Case Series

Ameloblastoma is a benign odontogenic tumor that exhibits local aggressiveness. Around 80% cases occur in the mandible, out of which the majority of cases are seen in the mandibular ramus region. Ameloblastoma presents as a non-symptomatic lesion and may be detected during routine radiographic examination. However, the diagnosis is confirmed by histopathological examination. In our case series, we report three cases of Ameloblastoma: one in the maxilla and two in the mandible, of which one was in the ramus region and the other in the anterior region. All lesions were confirmed by histopathological examination with immunohistochemical staining. Histologically, Ameloblastoma has multiple microscopic variants. In our study, we found a follicular variant in the maxilla, a desmoplastic variant in the mandibular ramus, and a follicular and plexiform (mixed) pattern in the anterior mandible. In all three cases, there were varied clinical and radiographic findings. Thus, histopathological examination is a crucial confirmatory tool for accurate diagnosis and effective treatment planning.