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June 17, 2026Journal of Periodontal ResearchOpen Access

Diagnostic Accuracy Studies: Sensitivity, Specificity, and Beyond

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Authors

NVNancy VégasLFLisa FriedlanderJCJérémie F. Cohen

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Overview

Methodological article outlines diagnostic accuracy measures and evaluates clinical effectiveness of tests, suggesting broader assessments are needed.

Key Points

  • This article aims to outline key measures and challenges in evaluating diagnostic accuracy of medical tests.
  • Discusses sensitivity, specificity, and common biases in diagnostic accuracy studies.
  • Highlights examples from clinical, radiographic, and biomarker tests, as well as AI-based approaches.
  • Explores the need for assessments beyond accuracy, including feasibility and patient outcomes.
  • Emphasizes that diagnostic accuracy is a preliminary evaluation step, not the sole measure of effectiveness.
  • Identifies biases and variability that can affect diagnostic test results.
  • Advocates for evaluation methods that incorporate clinical impact and patient-centered outcomes.

Cite This Study

Végas et al. (2026) studied this question.

synapsesocial.com/papers/6a323b4cd50b63ecad205ff0https://doi.org/10.1111/jre.70128
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