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This review describes the genetic diversity, clinical features, and neuropathology of spinocerebellar ataxias, indicating the importance of comprehensive understanding.
This review describes the clinically and genetically heterogenous group of 52 Spinocerebellar ataxias (SCAs). After a brief description of the epidemiology and clinical spectrum, this review highlights the functional neuroanatomy, the need for sufficient sampling based on this knowledge, and showcases examples of neuropathology. In addition, a comprehensive overview of the pathogenesis of the different forms of spinocerebellar ataxias (SCAs) is given.
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Vries et al. (2026) studied this question.
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