What question did this study set out to answer?

This study aims to examine the relationship between ABO blood groups and clinical outcomes in COVID-19 patients.

June 17, 2026Scientific ReportsOpen Access

Association between ABO blood groups and clinical manifestations and outcomes of COVID-19: a retrospective cross-sectional study in southeast Iran

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Authors

SBSadegh Valinejad BolghanIslamic Azad University, Karaj NMNastaran MirabutalebiIran University of Medical Sciences FKFatemeh KhaliliIslamic Azad University of Tabriz

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Implication

Retrospective study explores ABO blood group associations with clinical features and outcomes in COVID-19 patients, suggesting blood type impacts disease severity.

Key Points

This study aims to examine the relationship between ABO blood groups and clinical outcomes in COVID-19 patients.
Retrospective cross-sectional study of 894 RT-PCR–confirmed COVID-19 patients
Analyzed demographic and clinical data, including ABO blood groups and comorbidities
Used chi-square, Kruskal–Wallis, and multivariable logistic regression for statistical analysis
Blood group AB showed significantly fewer symptoms (aOR = 0.68, 95% CI 0.47–0.98) compared to other groups.
Hospitalization rates were highest in group O (P = 0.003).
Significant associations between blood groups and symptoms like fever, cough, and gastrointestinal issues (all P < 0.05).

Cite This Study

Bolghan et al. (2026) studied this question.

synapsesocial.com/papers/6a323c94d50b63ecad206be8 https://doi.org/10.1038/s41598-026-57710-z

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Implication

Retrospective study explores ABO blood group associations with clinical features and outcomes in COVID-19 patients, suggesting blood type impacts disease severity.

Association between ABO blood groups and clinical manifestations and outcomes of COVID-19: a retrospective cross-sectional study in southeast Iran

Discussion

Member takes

Implication

Key Points

Cite This Study

Association between ABO blood groups and clinical manifestations and outcomes of COVID-19: a retrospective cross-sectional study in southeast Iran

Discussion

Member takes

Implication

Key Points

Cite This Study

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