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Diagnostic Accuracy of USG / CT ‐Guided FNAC With Rapid On‐Site Evaluation in Nodular Liver Lesions: Cytology–Histopathology Correlation

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Randomized trial shows high diagnostic accuracy in nodular liver lesions, suggesting effective early disease detection.

To evaluate the diagnostic accuracy of USG/CT-guided FNAC with rapid on-site evaluation for nodular liver lesions.
Forty-seven patients with nodular liver lesions diagnosed by USG/CT imaging underwent FNAC with ROSE and subsequent trucut biopsy.
The study spanned 18 months and included patients aged 30-85 years.
FNAC showed a sensitivity of 95.10% and specificity of 83%.
Positive predictive value was 97.50% and negative predictive value was 71.40%.
Overall diagnostic accuracy was 93%, with hepatocellular carcinoma being the most common finding.

Jeny et al. (2026) studied this question.

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