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June 17, 2026Open Access

A Brief Review on Drug Use in Treatment of Hiv

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Authors

AKAbhijit P. Borkar*, Anushree A. Dhole, Shreya A. Dhurandhar, Khemu G. Shedame, Dr. Manisha D. Kitukale

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Overview

Systematic review analyzes Idvynso's safety and efficacy for HIV-1 treatment, indicating promising outcomes for patients.

Key Points

  • This systematic review aims to evaluate the efficacy, safety, and pharmacological profile of Idvynso for HIV treatment.
  • Literature review of pharmacological studies focusing on Idvynso (doravirine + islatravir) for HIV-1 treatment in adults.
  • Analysis of Phase 3 trial results (Trial 051, Trial 052).
  • Evaluation of pharmacology and comparison with existing three-drug combinations.
  • Idvynso achieves non-inferior virologic suppression compared to traditional triple-drug therapies (e.g., Biktarvy).
  • Limited central nervous system side effects noted for doravirine, improving patient adherence.
  • Islatravir's features allow a prolonged effect while minimizing concerns of lymphocyte depletion.

Cite This Study

Abhijit P. Borkar*, Anushree A. Dhole, Shreya A. Dhurandhar, Khemu G. Shedame, Dr. Manisha D. Kitukale (2026) studied this question.

synapsesocial.com/papers/6a323d57d50b63ecad20703dhttps://doi.org/10.5281/zenodo.20695878
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