What question did this study set out to answer?

This review investigates the relationship between depressive symptoms and sleep quality in patients with multiple sclerosis (MS).

June 17, 2026BMC NeurologyOpen Access

The association between depressive symptoms and sleep quality in patients with multiple sclerosis: a systematic review and meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

AMAfshin MoradiTabriz University of Medical Sciences AEAsal EbrahimianTabriz University of Medical Sciences MTMahnaz TalebiImam Reza Hospital

Discussion

Member takes

Implication

Systematic review finds moderate correlation between depressive symptoms and sleep quality in multiple sclerosis, indicating need for further research.

Key Points

This review investigates the relationship between depressive symptoms and sleep quality in patients with multiple sclerosis (MS).
Systematic search of PubMed, Embase, Web of Science, and Scopus up to February 2025.
Included studies assessed depressive symptoms using validated scales and sleep quality via the Pittsburgh Sleep Quality Index.
Twenty-one studies with 3,144 patients were included for meta-analysis.
Moderate positive correlation found between sleep quality and depressive symptoms (r = 0.46, 95% CI: 0.37–0.55, p < 0.01).
Considerable heterogeneity observed (I² = 83.3%).
Low certainty of evidence due to observational study nature and substantial inconsistency.

Cite This Study

Moradi et al. (2026) studied this question.

synapsesocial.com/papers/6a323d93d50b63ecad207240 https://doi.org/10.1186/s12883-026-05075-1

View Full Paper

Ask AI

Bookmark

Implication

Systematic review finds moderate correlation between depressive symptoms and sleep quality in multiple sclerosis, indicating need for further research.

The association between depressive symptoms and sleep quality in patients with multiple sclerosis: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

The association between depressive symptoms and sleep quality in patients with multiple sclerosis: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider