Demonstrates efficient C-H arylation of unactivated arenes using a potassium tert-butoxide/gatifloxacin hydrochloride catalyst, indicating a novel synthetic approach.
A transition-metal-free protocol for the efficient construction of biaryl frameworks via direct C–H arylation of unactivated arenes with aryl halides is reported, enabled by a synergistic potassium tert-butoxide (t-BuOK)/gatifloxacin hydrochloride...
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Song et al. (2026) studied this question.
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