Case series highlights the impact of renal osteodystrophy on facial structure in chronic renal disease, suggesting early management is critical.
Chronic renal disease (CRD) is a progressive, irreversible loss of renal mass and function, posing a significant health concern. Secondary hyperparathyroidism caused by hypokalcemia in CRD often leads to renal osteodystrophy (ROD), a bone pathology resulting from alterations in mineral metabolism. ROD typically occurs early in renal failure and progresses as kidney function deteriorates. Marked jaw enlargement remains a rare but severe complication of the ROD, causing significant facial disfigurement. This case series highlights the four cases of ROD with extensive orofacial involvement, emphasizing the importance of early diagnosis and management.
No takes yet. Share an insight, caveat, or question.
Nivetha et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: