What question did this study set out to answer?

This research aims to estimate the pooled prevalence of inappropriate antibiotic use and its associated factors among hospitalized patients in Ethiopia.

June 17, 2026Exploratory Research in Clinical and Social PharmacyOpen Access

Inappropriate antibiotic utilization in hospitalized patients in Ethiopia: A systematic review and meta-analysis

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Authors

TATekletsadik Tekleslassie AlemayehuAddis Ababa University EGEskedar Dires GebremeskelUniversity of Gondar BTBezawit Dereje TilahunUniversity of Gondar

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Implication

Systematic review estimates high rates of inappropriate antibiotic use among hospitalized patients, highlighting urgent needs for improved stewardship.

Key Points

This research aims to estimate the pooled prevalence of inappropriate antibiotic use and its associated factors among hospitalized patients in Ethiopia.
Conducted a systematic review and meta-analysis following PRISMA guidelines
Conducted comprehensive literature searches across multiple databases and grey literature
Utilized a random-effects model to estimate pooled prevalence and assessed heterogeneity using the I 2 statistic.
Pooled prevalence of inappropriate antibiotic use estimated at 40.50% (95% CI: 24.88–56.16)
Inappropriate indication (26.2%) and incorrect duration of therapy (24.65%) were most common
Significant associations found with comorbid conditions (OR = 3.46; 95% CI: 2.79–4.28) and multiple medications (OR = 2.98; 95% CI: 2.31–3.84).

Cite This Study

Alemayehu et al. (2026) studied this question.

synapsesocial.com/papers/6a323e9ed50b63ecad207d84 https://doi.org/10.1016/j.rcsop.2026.100809

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Implication

Systematic review estimates high rates of inappropriate antibiotic use among hospitalized patients, highlighting urgent needs for improved stewardship.

Inappropriate antibiotic utilization in hospitalized patients in Ethiopia: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Inappropriate antibiotic utilization in hospitalized patients in Ethiopia: A systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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