Key result
An RV GLS/sPAP below the median was associated with a significantly shorter survival time in patients with fibrotic interstitial lung diseases (61 vs. 74 months, p=0.01).
Why the study?
Right ventricle to pulmonary circulation coupling is an indicator of RV performance, but data regarding its non-invasive echocardiographic assessment in fibrotic interstitial lung diseases were lacking.
Does non-invasive echocardiographic assessment of right ventricle to arterial coupling predict survival in patients with fibrotic interstitial lung diseases?
Comparison
f-ILD patients vs healthy controls, and RV GLS/sPAP below vs above median
Design
Observational cohort study
Follow-up
Mean 70 ± 4 months
Authors
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RV GLS/sPAP may stratify prognosis in f-ILD; leaves open its clinical utility pending prospective validation.
Observational (n=80)
Does non-invasive echocardiographic assessment of right ventricle to arterial coupling predict survival in patients with fibrotic interstitial lung diseases?
Absolute Event Rate: 61% vs 74%
p-value: p=0.01
Non-invasive echocardiographic assessment of right ventricular to pulmonary arterial coupling (RV GLS/sPAP) is an independent predictor of survival in patients with fibrotic interstitial lung disease.
Santoro et al. (2022) conducted an observational in Fibrotic interstitial lung diseases (f-ILD) (n=80). Low RV GLS/sPAP (below median) vs. RV GLS/sPAP above median was evaluated on survival time (p=0.01). An RV GLS/sPAP below the median was associated with a significantly shorter survival time in patients with fibrotic interstitial lung diseases (61 vs. 74 months, p=0.01).
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