Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response

Keep reading

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese MiceOriginal Research · 2008 · 1,164 citations
2. 2Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to KetosisOriginal Research · 2009 · 363 citations
3. 3Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injuryCohort Study · 2017 · 148 citations
4. 4Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 actionOriginal Research · 2015 · 77 citations