Key result
Type III hyperlipoproteinaemia is linked to higher rates of peripheral occlusive arterial and coronary disease.
Observational (n=18)
Eighteen patients with type III hyperlipoproteinaemia, diagnosed on the basis of skin lesions, serum lipids, and lipoprotein electrophoresis, have been fully investigated over a period of 15 years. The incidence of coronary artery disease was only slightly increased, and was not increased at all among first-degree relatives. Peripheral occlusive arterial disease was probably more common. An increased incidence of carbohydrate intolerance was found in neither the patients nor their relatives. The effects of treatment on the skin were uniformly good.
No takes yet. Share an insight, caveat, or question.
Peter Borrie (1969) conducted an observational in Type III hyperlipoproteinaemia (n=18). Type III hyperlipoproteinaemia vs. First-degree relatives (for some outcomes) was evaluated on Incidence of coronary artery disease, peripheral occlusive arterial disease, and carbohydrate intolerance. Type III hyperlipoproteinaemia was associated with a slightly increased incidence of coronary artery disease and more common peripheral occlusive arterial disease over a 15-year period in 18 patients.
Synapse has enriched 5 related papers. Consider them for comparative context: