Amplification of carotid sinus activity using an electric analog resulted in larger sinusoidal excursions in arterial pressure in response to vagus nerve stimulation compared to without amplification.
Amplification of carotid sinus activity of a dog is brought about through the use of an electric analog of the carotid sinus applied in parallel with this element of the dog's own pressure regulating system. Sinusoidal excursions in arterial pressure in response to corresponding variations, between fixed limits, in rate of stimulus of one vagus nerve were larger with carotid sinus amplification than without it. Evidence presented supports the concept that because of the delay in the response of arteriolar smooth muscle, effective buffering of sudden variations in arterial pressure cannot be accomplished by variations in resistance, but can be through variations in flow.
Homer R. Warner (Wed,) conducted a other in Blood pressure regulation. Electric analog of the carotid sinus vs. Without carotid sinus amplification was evaluated on Sinusoidal excursions in arterial pressure in response to variations in rate of stimulus of one vagus nerve. Amplification of carotid sinus activity using an electric analog resulted in larger sinusoidal excursions in arterial pressure in response to vagus nerve stimulation compared to without amplification.