Population
Helically cut strips of rabbit carotid artery
Comparison
Potassium-free Krebs solution, cardiac… vs Standard conditions/baseline
Design
Preclinical
Authors
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May alter interpretations of glycoside vascular effects; leaves open translation from rabbit artery models to human therapeutics.
Cardiac glycosides and potassium-free media increase contractile tension in rabbit carotid artery strips, suggesting a mechanism related to intracellular electrolyte alteration and loss of muscle fiber potassium.
Edward J. Leonard (1957) studied this question.
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