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January 1, 1972The Japanese Journal of PharmacologyOpen Access

Contractile Responses of Isolated Rabbit Aortae to Transmural Stimulation as Affected by Calcium, Strontium, Sodium and Ouabain

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Population

Isolated rabbit aortae

Design

Preclinical

Authors

NTNoboru TodaToyama College

Discussion

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Implication

Biphasic Ca2+ effects on aortic contraction seen in vitro; leaves open relevance to human vascular regulation.

Structured PICO

P
Population
Isolated rabbit aortae
I
Intervention
Transmural stimulation with varying concentrations of Calcium, Strontium, Sodium, and Ouabain
O
Outcome
Contractile responsessurrogate

Cite This Study

Noboru Toda (1972) studied this question.

synapsesocial.com/papers/6a7e90cc24fafc1ad4ea44b1https://doi.org/10.1016/s0021-5198(19)31669-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vascular Smooth Muscle: Dual Effect of Calcium1963 · 285 citations
  2. 2Role of Calcium in Contractile Excitation of Vascular Smooth Muscle by Epinephrine and Potassium1962 · 67 citations
  3. 3Calcium effect on performance of the heart1962 · 44 citations
  4. 4CONTRACTILE RESPONSES OF SPIRAL STRIPS OF LARGE BLOOD VESSELS FROM RABBITS TO TRANSMURAL STIMULATION AND TYRAMINE1972 · 6 citations
  5. 5Uptake of Tritium-Labeled Norepinephrine in Brain and Other Tissues of Cat in vitro1961 · 136 citations