January 1, 1977The Japanese Journal of PhysiologyOpen Access

Contractile Behaviour of Cardiac Ventricular Muscle in Strontium Solution

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Population

Bullfrog ventricular muscle preparation

Comparison

Calcium-free Strontium (Sr) Ringer solution vs Calcium (Ca) Ringer solution

Design

Preclinical

Authors

HKHiroshi KawataHigh Energy Accelerator Research Organization JHJunna HataeFukuoka University

Discussion

Member takes

Implication

Strontium-calcium substitution in amphibian myocardium is hypothesis-generating; leaves open relevance to mammalian hearts or any clinical application.

Structured PICO

Population

Bullfrog ventricular muscle preparation

Intervention

Calcium-free Strontium (Sr) Ringer solution

Comparator

Calcium (Ca) Ringer solution

Outcome

Contractility (rate of rise of twitch tension, time to peak tension, action potential duration)surrogate

Strontium can replace calcium in maintaining the electrical and mechanical activities of bullfrog ventricular muscle, though with altered kinetics and contracture patterns.

Cite This Study

Kawata et al. (1977) studied this question.

synapsesocial.com/papers/6a729bfc87f9210571289e87 https://doi.org/10.2170/jjphysiol.27.167

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Implication

Strontium-calcium substitution in amphibian myocardium is hypothesis-generating; leaves open relevance to mammalian hearts or any clinical application.

Contractile Behaviour of Cardiac Ventricular Muscle in Strontium Solution

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Contractile Behaviour of Cardiac Ventricular Muscle in Strontium Solution

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider