October 1, 1989Cardiovascular Research

Electrical and mechanical effects of strontium in sheep cardiac Purkinje fibres

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Population

Sheep cardiac Purkinje fibres perfused in vitro

Design

Preclinical

Authors

MGM. D GONZALEZState University of New York MVMario VassalleState University of New York

Discussion

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Implication

Sheep Purkinje fiber data are hypothesis-generating; leaves open strontium effects in human myocardium or in vivo models.

Structured PICO

Population

Sheep cardiac Purkinje fibres perfused in vitro

Intervention

Strontium (1.35-10.8 mmol.litre-1) in a nominally calcium free solution

Outcome

Electrical and mechanical effects (action potential characteristics, twitch amplitude, tonic force)surrogate

In sheep cardiac Purkinje fibres, strontium induces pronounced electrical and mechanical changes due to enhanced influx and electrogenic Na-Sr exchange.

Cite This Study

GONZALEZ et al. (1989) studied this question.

synapsesocial.com/papers/6a7db0f0629c956ef7ac7f3a https://doi.org/10.1093/cvr/23.10.867

View Full Paper

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Bookmark

Electrical and mechanical effects of strontium in sheep cardiac Purkinje fibres

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Electrical and mechanical effects of strontium in sheep cardiac Purkinje fibres

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider