Key result
Larger preoperative left atrium linked to ~86% lower postoperative mortality in pediatric TAPVC repair.
Why the study?
TAPVC is a rare congenital heart defect, and this study aimed to investigate how specific echocardiographic and morphological characteristics impact prognosis to improve risk stratification and management strategies.
Cohort (n=48)
Yes
Odds Ratio: 0.143 (95% CI 0.024–0.857)
p-value: p=0.033
In children undergoing surgical correction of TAPVC, a smaller left atrium (≤ 0.85 cm) and the presence of preoperative pulmonary venous obstruction are significant predictors of postoperative mortality and obstruction.
Small LA size (≤0.85 cm) and preoperative PVO may signal higher postoperative death/PVO risk in pediatric TAPVC; leaves open need for prospective validation.
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart defect where the pulmonary veins abnormally connect to the systemic venous circulation, rather than the left atrium (LA). This study retrospectively analyzed 48 children diagnosed with TAPVC from January 2014 to January 2024 to investigate how specific echocardiographic and morphological characteristics impact prognosis. Perioperative records, including echocardiography, computed tomography angiography (CTA) images, surgical details, and patient outcomes, were reviewed. Data were statistically analyzed using tools such as t-tests, Mann-Whitney U tests, χ² tests, and logistic regression. Key factors examined included age at surgery, anatomical subtype of TAPVC, presence of preoperative obstruction, surgical techniques used, and postoperative complications. By identifying the impact of these variables on survival rates and hospital recovery, the study aims to improve risk stratification and management strategies for better outcomes in children with TAPVC.
No takes yet. Share an insight, caveat, or question.
Xue et al. (2025) conducted a cohort in Total anomalous pulmonary venous connection (TAPVC) (n=48). Left atrium size > 0.85 cm vs. Left atrium size ≤ 0.85 cm was evaluated on Postoperative death (OR 0.143, 95% CI 0.024-0.857, p=0.033). A preoperative left atrium size greater than 0.85 cm was independently associated with a significantly reduced risk of postoperative death (OR 0.143) in children undergoing surgical correction of TAPVC.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: