A rare case of adult neuroblastoma presenting with cervical lymphadenopathy: Diagnostic and therapeutic challenges

Although neuroblastoma is common in children, it is rarely seen in adults. In this case report, a 24-year-old female patient was found to have an adrenal tumor after presenting with constitutional symptoms and painless cervical lymphadenopathy. Neuroblastoma was diagnosed by immunohistochemistry and histopathology. However, even after she received conventional chemotherapy, the illness worsened, and she had to be referred for genomic profiling and I-131 metaiodobenzylguanidine therapy. This case emphasizes the limitations of traditional chemotherapy in adults, the requirement of advanced diagnostic and treatment techniques, and the importance of including neuroblastoma as the differential diagnosis of small round blue cell tumors in young adults. It also underscores the growing relevance of molecular profiling and radionuclide therapy in the management of such cases.