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Demonstrates TMEM16E-mediated cell survival during acidic stress, indicating its importance in cell signaling.
clearance pathways. Using wound healing and MTS assays, we demonstrated that TMEM16E expression significantly enhances cell proliferation and survival under acidic conditions. Our findings underscore the importance of TMEM16E-mediated macropinocytosis in maintaining plasma membrane integrity and promoting cell survival, highlighting its role as a crucial signaling pathway in both physiological and pathological contexts.
Kim et al. (2026) studied this question.
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