Randomized trial identifies factors influencing depression remission in patients using measurement-based care, suggesting integration of treatments.
Key Points
This research aims to identify factors that influence the response and remission rates in depression treatment using measurement-based care.
Analyzed electronic health records of 4778 patients aged 12+ from an academic outpatient psychiatry clinic.
Included patients with baseline PHQ-9 scores > 9 and at least one follow-up measurement.
Utilized Cox regression models to evaluate associations, adjusting for demographics and clinical covariates.
Response rate was 46.3%; remission rate was 28.2%.
Associated factors for response included combined treatment (HR = 1.189, p = 0.014) and timely follow-up PHQ-9 within 4–9 months (HR = 1.303, p < 0.001).
Key factors for faster remission included combined psychiatry and psychotherapy (HR = 1.189, p = 0.014), timely follow-up (HR = 1.255, p = 0.002), and absence of PTSD (HR = 0.751, p = 0.010).