What question did this study set out to answer?

This study aims to investigate the relationship between sleep disturbances, treatment-related adverse events, and psychological distress in breast cancer patients.

June 18, 2026Patient Preference and AdherenceOpen Access

Sleep Disturbance, Treatment-Related Adverse Events, and Psychological Distress in Breast Cancer Patients: A Prospective Cohort Study

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Authors

FZFang ZhaoChinese Academy of Medical Sciences & Peking Union Medical College YLYuqiu LiShandong University of Traditional Chinese Medicine YZYi ZhouShihezi University

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Implication

Prospective cohort study analyzes sleep quality's impact on treatment-related adverse events in breast cancer patients, indicating significant correlations.

Key Points

This study aims to investigate the relationship between sleep disturbances, treatment-related adverse events, and psychological distress in breast cancer patients.
Prospective cohort study involving 300 female breast cancer patients from two medical centers in China.
Assessments included the Pittsburgh Sleep Quality Index and Symptom Checklist-90 across treatment cycles.
Multivariable linear regression analyzed the relationships among sleep quality, psychological distress, and adverse events.
The baseline sleep disorder group showed higher treatment-related adverse events (P values < 0.05).
Baseline psychological distress was significantly correlated with total adverse events score (rs=0.54, P< 0.001).
In multivariate analysis, psychological distress was linked to increased adverse events (β=0.19, P< 0.001).

Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/6a338cf6630953a74978e1e4 https://doi.org/10.2147/ppa.s608376

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Implication

Prospective cohort study analyzes sleep quality's impact on treatment-related adverse events in breast cancer patients, indicating significant correlations.

Sleep Disturbance, Treatment-Related Adverse Events, and Psychological Distress in Breast Cancer Patients: A Prospective Cohort Study

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Implication

Key Points

Cite This Study

Sleep Disturbance, Treatment-Related Adverse Events, and Psychological Distress in Breast Cancer Patients: A Prospective Cohort Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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