Analysis of risk factors for bloodstream infections related to totally implantable venous access ports in breast cancer patients

Catheter-related bloodstream infection (CRBSI) is a significant complication of totally implantable venous access ports (TIVAP) used in breast cancer treatment. This study explores the risk factors for CRBSI in this patient group to inform prevention strategies. A retrospective analysis was conducted on 455 breast cancer patients treated with TIVAP between March 2021 and March 2024. Clinical data, including demographic, treatment-related, and catheter-specific factors, were analyzed. Univariate and multivariate logistic regression identified significant risk factors for CRBSI. Among the 455 patients, the incidence of CRBSI was 13.63%. Univariate analysis revealed significant associations between CRBSI and age, Karnofsky Performance Status at admission, education level, history of localized catheter infections within 3 months, and incisional infections (P < .05). However, multivariate analysis identified a history of localized catheter infections within 3 months as the sole independent risk factor (OR = 3.86, P < .001). A history of localized catheter infections within 3 months is an independent risk factor for CRBSI in breast cancer patients with TIVAP. Enhanced infection prevention strategies focusing on high-risk individuals are essential to reduce CRBSI incidence.