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This review aims to explore innovative strategies for drug delivery to the middle and inner ear, addressing significant barriers.

October 19, 2023Frontiers in PharmacologyOpen Access

Overcoming barriers: a review on innovations in drug delivery to the middle and inner ear

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Review discusses innovations in drug delivery systems for efficient treatment of ear disorders, highlighting novel approaches.

This review aims to explore innovative strategies for drug delivery to the middle and inner ear, addressing significant barriers.
Reviewed existing challenges in drug delivery for ear disorders like otitis media and sensorineural hearing loss.
Highlighted advancements in controlled release therapeutics and drug delivery devices such as hydrogels and microfluidic systems.
Discussed potential clinical applications of these novel delivery approaches.
Identified novel drug delivery methods that show promise in improving treatment efficacy for various ear disorders.
Demonstrated how localized delivery can circumvent bioavailability issues associated with conventional methods.
Presented advances in device-mediated delivery strategies that enhance drug accessibility to the middle and inner ear.

Delaney et al. (2023) studied this question.

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