OBJECTIVE: To assess bone mineral density (BMD) in men with steroid-treated rheumatoid arthritis (RA). METHODS: Dual-energy x-ray absorptiometry (DXA) was used to measure BMD in 40 men with RA, 20 of whom were receiving low-dose corticosteroids (< or = 10 mg prednisolone daily), and in 20 healthy, age-matched male controls. RESULTS: BMD was significantly reduced at the femoral neck and greater trochanter in both groups of RA patients, and at the spine from the anteroposterior dimension in the steroid-treated group. CONCLUSION: Low-dose steroid therapy may induce excess axial osteopenia in men with RA.
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Garton et al. (1993) studied this question.
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